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Other studies raise concerns about their safety for patients with advanced heart disease or heart failure

As much as 40% of all weight lost on GLP-1s is lean muscle, says Mahmoud Salama Ahmed, a medical chemist at Texas Tech University

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However, Wegovy has shown slightly more effectiveness in terms of weight loss in some studies, with patients losing an average of 15% of their body weight over 68 weeks compared to 10% for Ozempic users