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Funding This study was supported by the Medical Science Research Project of Hebei Provincial Health Commission in 2023 (20231400), the Basic Research Project of Chengde Science and Technology Bureau(202205B074) and the Hebei Province basic Research Project (Natural Science Foundation) (C2022406011)

Elsewhere in the hair follicle, several other cell cycle, DDR, apoptosis and ROS metabolising anti-oxidant markers appear to have very specific expression in specialised cell layers of the hair follicle, particularly those cells undergoing differentiation in the anagen-specific IRS during hair fibre formation