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with several inducers of gst-4 including H 2 O 2 and sodium azide being shown to be skn-1 dependent [118]

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KEAP1-independent NRF2 activators Given the complex regulation of the KEAP1-NRF2 system, it is not surprising that new pharmacological strategies are being explored, aimed at inducing NRF2 activity also in a KEAP1-independent manner

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