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This study was terminated due to high rates of dose modifications and early treatment discontinuation (NCT03729596)

Lets talk: The full results from Lillys ATTAIN-1 trial were published in the NEJM this week, evaluating orforglipron for obesity treatment

Common side effects of Saxenda include gastrointestinal symptoms such as nausea, vomiting, diarrhoea, and constipation, particularly during dose titration

Jennifer Manne-Goehler an obesity specialist with Mass General Brigham and consultant to the World Health Organization is concerned that people will access them and medicate themselves to meet a thinner ideal

Naltrexone has a half-life of 5 hours, and extended-release bupropion has a half-life of 21 hours, whereas weekly dosed GLP-1 receptor agonist medications have a half-life of 7 days, Rhodes said