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Discussion The findings of our meta-analysis revealed a significant reduction in body weight, waist circumference, BMI, and serious adverse events among antipsychotic-treated patients with schizophrenia

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The two main incretins are GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide, previously called gastric inhibitory polypeptide)

Mangiferin directly binds to Keap1, activates the downstream Nrf2/SLC7A11/GPX4 pathway, inhibits osteoblast ferroptosis, promotes bone formation and improves osteoporosis in ovariectomized mice and iron overload mice