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La semaglutida est aprobada por la FDA para mejorar el control glucmico en adultos con diabetes tipo 2 (Ozempic), para el manejo crnico del peso en adultos y adolescentes con obesidad o sobrepeso (Wegovy), y para reducir el riesgo de eventos cardiovasculares adversos mayores en pacientes con enfermedad cardiovascular establecida

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) improve biomarkers of inflammation and oxidative stress: A systematic review and meta-analysis of randomised controlled trials

The mechanism is based on enzymes such as nicotinamide adenine dinucleotide phosphate oxidase

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[DOI] [PubMed] [Google Scholar] McLean A