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In initial animal studies, that elucidated the role of glucose metabolism in insulin secretion, the rodent GLUT2 transporter was identified as the major sensor and transporter of glucose in pancreatic -cells

2025;21(9):e70639

The activity of the BCKD is controlled by phosphorylation, which inhibits the complex, and dephosphorylation, which activates the complex

We also thank our colleagues of the department of Health and Safety at NIZO food research and Professor Aalt Bast (Maastricht University, the Netherlands) for fruitful discussions

The dose-response behaviors of G protein signaling explored in this study (Fig