MicroRNA-218 (miR-218) released from dying motor neurons in ALS can directly modify astrocytes into disease-associated phenotypes (Hoye et al., 2018)
Maes M, Vandoolaeghe E, Neels H, Demedts P, Wauters A, Meltzer HY, et al
About 70% of patients with pernicious anemia have Type 1 IF antibodies
The clinically-used artemisinins, such as artemether, artesunate and dihydroartemisinin (DHA), are semisynthetic derivatives of the natural product artemisinin and possess a 1,2,4-trioxane core incorporating a peroxide bond that is essential for activity 2
One week post-injection, the mice were randomly divided into three groups, with 8 mice per group (24 mice in total): vehicle (group 1), 10 mg/kg J10 (group 2), and 20 mg/kg RK-33 (group 3, Ambeed, A179326)