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Notably, NUPR1, RGS4, ATG9B, GPX3, RBP2, ENTPD2, and CLDN4 were upregulated in pup livers, while TDO2, SLC25A25, MT-TT, NPMM2, MMD2, SLC0191, CXCL1, and CXCL9 were downregulated

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Given the scarcity of published literature in pancreatic NEN and relatively small sample sizes in the available literature, there is a need to study long-term outcomes in patients with this specific tumor