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Introduction Amyotrophic lateral sclerosis (ALS) is a complex multi-pathogenic neurodegenerative disorder primarily characterized by the loss of upper motor neurons in the brain and lower motor neurons in the spinal cord and the brain stem (Robberecht and Philips, 2013)

Maintaining an optimal GSH:GSSG ratio is essential for cell survival because GSH is one of the most important endogenous antioxidant defences, removing lipids and hydrogen peroxide

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Underscoring a distinct therapeutic relationship between BPC 157, this appears as a distinctive argument for BPC 157/angiogenesiss specific healing relationship and tissue-specific angiogenesis [8,16]