In a public warning on Thursday, Lilly said its own testing has unearthed potential safety issues in personalized forms of tirzepatide, the active ingredient in Zepbound
Heightened sensitivity can result in the perception of pain from non-painful stimuli (allodynia) and greater pain than would be expected from painful stimuli (hyperalgesia)
We will expand our portfolio with other promising therapies that represent important advances in medicine and patient care as well as strong commercial opportunities
Other external stressors similarly stimulate pro-inflammatory cytokine production, including chemical, metabolic, physical and social stressors
Even if the impact would be bigger than that, I think over a 10-year period, it will be manageable, and we will have adequate lead time to adjust and prepare for any changes that we see. On a more practical note, he said, Obesity rates around the world are very different, and we have one of the lowest exposures since 75% of our sales come from outside of the US and 40% of our sales are in emerging markets [where average BMIs are far lower]
