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Novel Approach to Skin Anti-Aging: Boosting Pharmacological Effects of Exogenous Nicotinamide Adenine Dinucleotide (NAD+) by Synergistic Inhibition of CD38 Expression

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Akt-mediated phosphorylation activates the kinase mammalian target of rapamycin complex 1 (mTORC1) activating its effector S6 kinase 1 (S6K1) involved in the up-regulation of protein synthesis and cell proliferation