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Metformin works primarily at the liver
Other common digestive side effects include: Vomiting: Often occurs alongside nausea, especially when starting treatment Diarrhea: Usually mild and temporary Constipation: Can occur as your digestive system adjusts Stomach pain: Typically mild and manageable Loss of appetite: While this contributes to weight loss, it can be concerning for some patients These digestive effects happen because GLP-1 slows how quickly food moves through your stomach
Appl Physiol Nutr Metab 2015;40:971-9.ArticlePubMed 31
However, the medication should be kept away from direct heat sources, such as radiators, windowsills with direct sunlight, or vehicle glove compartments
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