If you're conducting a short-term study, starting small with BPC-157 5 mg might be the best way to evaluate effectiveness
It just silenced that noise, if you will, Bunce says
NPJ Breast Cancer 10 , 40 (2024)
PMID: 78 KongF.ZhaoY.ZhangW.WangX.WuT.ZhouZ.et al
This interaction promotes M2 macrophage polarization, enhancing pro-tumorigenic phenotypes ( 4.3 Macrophage-ferroptosis immunometabolism Tumor-associated macrophages (TAMs) and ferroptotic cancer cells engage in a highly integrated, bidirectional metabolic dialogue that shapes immune outcomes and determines tumor ( + , increased transferrin receptor (TfR1) expression, and restricted ferroportin activity, thereby enriching the tumor microenvironment (TME) with redox-active iron ( Ferroptotic cancer cells reciprocally influence macrophage states by releasing DAMPs (HMGB1), oxidized phosphatidylethanolamines (SAPE-OOH), iron-loaded vesicles, and lipid peroxidation products that serve as signals to recruit, polarize, or reprogram macrophages ( Figure 5
