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The nominator generally expressed concern that the initial pricing by the contractor was inaccurate and did not appropriately consider the cost of the OCT device when provided by the independent diagnostic testing facility (IDTF)

As for CASP3, studies have shown a correlation between abnormal expression and BRCA patient prognosis, and an abnormal CASP3-mediated apoptosis pathway is a potential mechanism of chemoresistance in BRCA 40,41

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