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Patients should contact their GP or NHS 111 if they experience severe or persistent vomiting that prevents adequate fluid intake, as this may lead to dehydration and acute kidney injury, particularly in those with pre-existing renal impairment

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Researchers building escalation protocols should pair this page with our retatrutide dosing and titration protocol and the retatrutide vs semaglutide vs tirzepatide mechanism comparison

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Frequently Asked Questions What happens if I accidentally use an expired semaglutide injection