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In addition to the APC mutation, an AXIN2 mutation is also common in CRC

Most users report that nausea, diarrhea, and other gastrointestinal symptoms peak during the first few months of treatment and dose escalation, then gradually diminish

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This combination can accelerate fat loss for some patients, particularly those whose GLP1R and GIPR genetic variants (measured by PlexusDx's Precision Peptide Genetic Test) show high receptor sensitivity