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141,142 The holdase complex, consisting of BAG6, transmembrane domain recognition complex 35 (TRC35), and ubiquitin-like protein 4 A (Ubl4A), shields hydrophobic regions from a hydrophilic environment and prevents the formation of nondegradable protein aggregates

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Moreover, GPNMB has protective roles in the body by contributing to the resolution of inflammation and by inhibiting T cells activation 64,65

You might notice this as slight cloudiness in a solution that was previously clear