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[18] While higher levels of homocysteine have been associated with numerous health complications, levels of homocysteine that are too low can also be problematic and have been associated with peripheral neuropathy (often felt as hand and arm tingling) and an impaired ability to make glutathione, an important antioxidant that reduces inflammation in the body

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Most published research protocols use concentrations between 0.5mg/mL and 1.5mg/mL to balance dosing precision with stability

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However, as with any supplement, it's always advisable to consult with a healthcare professional before starting any new supplement regimen