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Routine Monitoring Per ADA Standards of Care The American Diabetes Association 2024 Standards of Care in Diabetes recommend comprehensive foot exams at least annually for all patients with type 2 diabetes, including monofilament testing and vibration sense assessment [2]
Mechanistically, GLP-1 receptor agonists may exert vascular protective effects by suppressing inflammation, limiting oxidative stress, and modulating key enzymes involved in extracellular matrix remodeling ( Matrix metalloproteinases, particularly MMP-9, together with their endogenous inhibitors (TIMPs), play central roles in extracellular matrix turnover and structural vascular remodeling ( The reduction in CRP, a recognized marker of aortic stiffness, medial degeneration, and systemic inflammation, further supports the anti-inflammatory profile associated with GLP-1RA therapy
But if your body struggles to absorb the nutrient, you may want to consider vitamin B12 injections since they bypass digestion completely (6)
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Juan Franco, first author of one of the reviews and researcher at Heinrich Heine University Dsseldorf, Germany, affiliated with the Iberoamerican Cochrane Network
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