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The more serious concern with sustained GH elevation is the theoretical risk of promoting growth of existing abnormal cells

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Similarly, oculomotor binocular dysfunction (HR 0.31, 95% CI: 0.160.60, p = 2 10 4 ), visual issues and blindness (HR 0.44, 95% CI: 0.260.76, p = 0.003), dry eye disease (HR 0.33, 95% CI: 0.150.71, p = 0.003), ametropic accommodative dysfunction (HR 0.31, 95% CI: 0.160.62, p = 2.3 10 4 ), and visual disturbances (HR 0.46, 95% CI: 0.260.83, p = 0.008) all showed statistically significant associations favoring Tirzepatide

"Alongside diet and exercise, over a year you would find that the average additional weight loss with orlistat was to the tune of 3-5 per cent of starting weight." Liraglutide also known as Saxenda Another GLP-1-based weight-loss drug

The trial result was impressive