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Yes....there are a whole host of drugs that impede the absorption of vitamin B12...and folate...and many others vitamins and minerals too (PPI's, H2 antagonists, and prednisilone is another prime example)

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It also serves as a cofactor for several enzymes involved in the biosynthesis of collagen, carnitine, and neurotransmitters, as well as in the metabolism of tyrosine and peptide hormones

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