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All participants also received lifestyle intervention, while those in STEP 3 additionally received intensive behavioral therapy

Second, while CYP3A4 was extensively validated in functional assays, other key markers of liver functionality, such as bile acid transporters and detoxification enzymes, were not examined in as much detail

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The menstrual cycle relies on a delicate balance of hormones, which can be disrupted by nutritional deficiencies or significant weight changes