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Modulation of HIF-1 and its upstream and downstream genes may contribute to the pathological processes of angiogenesis, inflammation, and complications such as calcinosis in DM patients (185, 189)

S1C, clusters 1, 3, and 19 represent TECs and enriched pathways of Metabolism pathways, Glyoxylate and dicarboxylate metabolism, PPAR signaling, and other pathways during the injury, which provided us with hints for subsequent studies

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Altered expression of CD4(+)CD25(+) regulatory T cells and its 5-HT(1a) receptor in patients with major depression disorder