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GLP-1 Receptor Agonist Market Restraints: High drug costs and manufacturing supply constraints limiting GLP-1 receptor agonist accessibility for patients globally GLP-1 receptor agonists' commercial success has created its own constraint: demand so far exceeds production capacity that patients with legitimate prescriptions cannot reliably obtain their medication

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1 Novo Nordisk, the maker of Ozempic and Wegovy , reported 26% higher operating profit last year as its obesity and diabetes treatments experienced double-digit growth

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The tissues were counterstained with DAPI (4,6-diamidino-2-phenylindole) for 10 min at room temperature to label the nuclei and then mounted on slides with anti-fade medium (ProLong Gold, Thermo Fisher Scientific Inc., Rockford, IL)