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Adapted from Wadden et al

Circulating mitochondrial DAMPs cause inflammatory responses to injury

Treatment with FARXIGA as monotherapy and in combination with metformin, glimepiride, pioglitazone, sitagliptin, or insulin produced statistically significant improvements in mean change from baseline at Week 24 in HbA1c compared to control

Interrupted sleep architecture means patients never reach the restorative sleep stages their bodies need, regardless of how many hours they spend in bed