The water retention is a sign creatine is working, and the muscle preservation benefits are worth far more than a temporary number on the scale
About 20% of people with MASLD develop liver inflammation known as metabolic dysfunctionassociated steatohepatitis (MASH)

Dietary modifications significantly impact tolerability: Consume smaller, more frequent meals rather than large portions Avoid high-fat, spicy, or heavily processed foods that may exacerbate nausea Maintain adequate hydration (1.52 litres daily for most people, though this may need adjustment for those with heart or kidney conditions) Increase dietary fibre gradually to support regular bowel movements Eat slowly and chew thoroughly, as gastric emptying is delayed Physical activity and postural support help address musculoskeletal symptoms: Engage in regular, moderate exercise including core-strengthening activities Consider physiotherapy assessment if back pain persists Maintain good posture and ergonomic practices, particularly during sedentary activities Use appropriate footwear and consider orthotics if biomechanical changes are significant Incorporate stretching and flexibility exercises into daily routines Pharmacological adjuncts may be appropriate for specific symptoms

This may involve any part of the oral mucosa but most frequently the buccal mucosa, affecting females and males equally [6, 14]
Thus, exploring the metabolic mechanisms involved becomes intriguing in the search for targeted therapies to enhance the immune response and protect against immune-mediated diseases