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Side effects associated with Rybelsus include: Digestive distress (nausea, abdominal pain, diarrhea, vomiting, constipation, heartburn, gastritis and GERD) Less common but more serious side effects include: Thyroid cancer Allergic reactions Kidney injury Gallstones Lowering the risk of Kidney Stones: A large trial compared different types of diabetes drugs with respect to the risk of kidney stones ( JAMA Internal Medicine , Jan

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One co-author reported relationships with CorEvitas, Formation Bio, and Burns White

Materials and Methods Mean percent change in weight from baseline, weight reduction 5% and mean change in glycated haemoglobin (HbA1c [%]) were compared between tirzepatide 10/15 mg (week 72, SURMOUNT2) and semaglutide 2.4 mg (week 68, STEP 2) applying the Bucher method to the efficacy estimand