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Olympus, Tokyo, Japan) and continuously superfused at a flow speed of 1 mL/min with a bath solution containing 140 mM NaCl, 5 mM KCl, 1 mM CaCl 2 , 2 mM MgCl 2 , 10 mM HEPES, and 10 mM glucose, adjusted to pH 7.4 with NaOH

Fournier's gangrene (necrotising fasciitis of the genitalia) is a rare but serious infection that has been reported with SGLT2 inhibitors

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Patients said that the drugs loosened the grip of their addictions to drugs, cigarettes, alcohol and sex

Over time, newer agents improved both convenience and effectiveness