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Lloyd, D., Eshantha, L., Salgado, J., Turner, M

349 If the ulcers fail to show a 50% reduction after 4 weeks of appropriate management via conventional methods, several advanced therapies, including negative-pressure therapy, growth factor therapy, bioengineered tissue, acellular matrix tissue, stem cell therapy, hyperbaric oxygen therapy, and, most recently, topical oxygen therapy, can be considered

Give one properly formulated, FSSAI-compliant product a full month before deciding it "isn't working." This last point echoes what ICMR-NIN's own Dietary Guidelines for Indians (2024) emphasise more broadly: sustainable, consistent habits not one-off fixes are what actually move the needle on nutrition outcomes

27, 28, 29 Tyrosinemia types II and III variably respond to tyrosine-restricted diet therapies, unlike the liver and renal disease of HT-1

References Siegel RL, Miller KD, Fuchs HE, Jemal A