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Initial hormone shifts : Some patients begin to notice improvements in skin, hair patterns, or cycle regularity

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Olfatifar M, Zali MR, Pourhoseingholi MA, Balaii H, Ghavami SB, Ivanchuk M, et al

With seven additional phase 3 readouts expected in 2026, we believe retatrutide could become an important option for patients with significant weight-loss needs and certain complications, including knee osteoarthritis." Safety data The most common adverse events with retatrutide were nausea, diarrhea, constipation, vomiting and decreased appetite