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Thus, gene therapy with viral vectors protects from neuronal death in animal models of ALS (Lee et al., 2019) and cerebral ischemia (Hayashi et al., 2001), promotes angiogenesis, and reduces apoptosis in SCI (Kitamura et al., 2007)

[7] Research, including early-phase clinical trials, demonstrated that AOD 9604 reduced up to 1.5 kg of body weight over 12 weeks in obese subjects when combined with a caloric deficit, with a favorable safety profile

Focus on the molecular mechanisms of cisplatin resistance based on multi-omics approaches

& Pela, I

Besides, in ketogenic dietary interventions, FGF-21 reduces IL-1 secretion by macrophages, further alleviating systemic inflammation and metabolic dysfunction [256]