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635 The depressed mice induced by intermittent alcohol consumption showed significant iron deposition, increased TFRC expression, and decreased GPX4 expression in the hippocampus and prefrontal cortex

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Overexpression of FSP1 effectively inhibited ferroptosis in HT1080 cells but failed to inhibit ferroptosis in COQ2-deficient cells, which indicates that the anti-ferroptosis effect of FSP1 is dependent on CoQ10