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the compound's evidence base is limited to preclinical in vitro and animal (largely rodent) studies of IGF-1 receptor activation, muscle-cell signaling, and tissue repair, with human safety and efficacy data for this specific analog effectively absent

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It has been shown that a combination of zinc and a zinc-ionophore pyrithione could inhibit the replication of the SARS-CoV virus in vitro via virus polymerase inhibition (197)

Genetic polymorphisms of human N-acetyltransferase, cytochrome P450, glutathione-S-transferase, and epoxide hydrolase enzymes: relevance to xenobiotic metabolism and toxicity