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doi:10.1001/jama.2021.23487 Frias, J

This central adiposity carries greater health implications, including elevated risks for cardiovascular disease and type 2 diabetes

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All of the above suggest that abnormal dietary intake and defective metabolism of Met could result in the abnormal levels of Met and its metabolites (SAMe and GSH) and accumulation of toxic metabolic intermediates (Hcy, Hcythiolactone, and 3-MTP) in the liver, which in turn affects the functions and the inflammatory responses to damage/infection of the liver (Figure 4)

"With superior absorption and bioavailability, liposomal glutathione is the most effective supplemental form