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Measure pain levels, range of motion, and strength every 7 to 14 days using simple scales and movement tests

Microbial metabolic networks at the mucus layer lead to diet-independent butyrate and vitamin B12 production by intestinal symbionts mBio 2017;8(5):e00770-17 doi:10.1128/mBio.00770-17 (Laboratory co-culture study

Three residues, tyrosine on the proximal side of the heme (Tyr415 in HPII) and histidine and asparagine on the distal side (His128 and Asn201 in HPII), are believed to be essential for catalysis [30]

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This suggests that the buffering capacity of the vaginal milieu is different from that of culture medium or that the contribution of lactic acid to the vaginal acidic pH is only partial