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Overall, there is strong evidence suggesting that CCK can impact energy and glucose homeostasis by activating a gutbrain vagal pathway

These side effects often improve with dose timing, food intake, hydration, or slower titrationnot avoidance

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The delayed gastric emptying may potentially lead to gastro-oesophageal reflux, which could contribute to an unpleasant taste sensation

This is especially relevant during perimenopause, when hormonal fluctuations disrupt the delicate balance of your gut bacteria