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10.1111/j.1471-4159.2009.06319.x 18 ChaiY.-C.MieyalJ

The development of an optimal therapy is, however, complicated by certain side effects, including the possibility of post-treatment hypothyroidism and recurrence of hyperthyroidism following an initial successful treatment

Dual-pathway brightening, not single-step: Most body brighteners address only melanin distribution or production

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These compounds typically regulate several biological pathways, including the monoamine neurotransmitter system and the hypothalamicpituitaryadrenal (HPA) axis, thereby effectively alleviating depressive symptoms [6, 7]