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reported the presence of HIF-1 within the muscle fibers of DM patients, the firefly/kidney assay suggested that retinoic acid-inducible gene I (RIG-I), a newly described HIF-induced gene containing HRE, was essential for the transcriptional response to hypoxia after RIG-I removal (187)

Available current research evidence indicates that neuroinflammation clearly contributes to the neurodegeneration in several neurodegenerative diseases (Glass et al., 2010

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