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After 90 days of treatment, animals were humanely euthanized, and knee joint tissues were harvested, fixed, decalcified, paraffinembedded, sectioned, and examined using hematoxylineosin staining, immunohistochemical analysis, and immunofluorescence microscopy

Clean Technol Environ Policy 25:20252037

Spatiotemporal multiplexed immunofluorescence imaging of living cells and tissues with bioorthogonal cycling of fluorescent probes

doi: 10.1007/s12640-023-00654-3 49 LamPNewlandJFaullRLMKwakowskyA

The main skin lightening mechanism is thought to be inhibition of tyrosinase which shifts melanogenesis from eumelanin (darker) to phaeomelanin (lighter) synthesis