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Gastrointestinal side effects are most common during the titration phase, when doses are increasing

[14] [15] The relationship between diabetes and erectile function is multifactorial, involving vascular, neurological, hormonal, and psychological mechanisms that collectively impair the ability to achieve or maintain an erection sufficient for sexual activity

2.3 Study Design and Pharmacokinetic Sampling This was a multicenter, single-dose, open-label, parallel-group study (ClinicalTrials.gov identifier NCT00833716) conducted in accordance with Good Clinical Practice [32], the Declaration of Helsinki, and relevant guidelines for studies in patients with RI [33, 34]

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Focus on: Stress management and mindfulness practices to reduce emotional eating Getting enough sleep, since fatigue and stress can both increase appetite Staying connected with supportive friends and family 10