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Mandel, R.P

D) Conjugation strategies Conjugating peptides to larger molecules are also a method that has become quite popular in recent years, which not only increase lipophilicity, but the enhanced steric hindrance also prevents filtration of the conjugate through the kidneys and prolongs circulation time

Among other glucose-lowering agents added to GLP-1RA, a propensity score-matched cohort study [52] demonstrated a meaningful reduction in heart failure hospitalization in those with SGLT-2i and GLP-1RA compared to those taking a combination of sulfonylurea medications and GLP-1RA