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doi:10.1001/jama.2026.0287 To view or add a comment, sign in Mechanistic Comparison of Single, Dual, and Triple Incretin-Based Agonists The progressive mechanistic complexity and metabolic efficacy of modern incretin-based therapies, moving from single to dual and triple receptor agonism

10.1136/bmj.k1497 40 YangB.LiS.ChenZ.FengF.HeL.LiuB.et al (2020)

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Jebb emphasized that GLP-1 drugs "are a really valuable tool in obesity treatment but obesity is a chronic relapsing condition." "One would expect that these treatments need to be continued for life, just in the same way as blood pressure medication," Jebb said