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A placebo-controlled study utilizing the device as treatment for type 2 diabetes was terminated prematurely because of a ~3% incidence of hepatic abscess in subjects using the device (77)
The ability to switch from glucagon to GLP-1 in times of metabolic stress may be a critical way the body maintains blood sugar control.
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For weight management , NICE technology appraisals TA875 (semaglutide 2.4mg, Wegovy) and TA664 (liraglutide 3.0mg, Saxenda) specify different continuation criteria and require specialist service involvement
It gets harder to keep a calorie deficit when alcohol is involved
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