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For example, the role of macrophages in inflammation has moved away from the dichotomy of pro-inflammatory M1 and anti-inflammatory M2 cells, being replaced by a more nuanced view, encompassing a diversity of heterogeneous macrophage sub-types, likely with specialized functions [36]

doi: 10.1046/j.1526-4610.2003.03006.x 17

You cannot simply resume your previous dose without risking severe side effects

A study on gamma-glutamyl transferase (GGT) in non-ST elevation acute coronary syndrome (NSTE-ACS) and its correlation with angiographic severity and cardiac events