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While effective for managing diabetes and aiding in weight loss, these medications are proving to cause a range of gastrointestinal issues, such as nausea, vomiting, diarrhea, and severe abdominal pain

For diabetes patients, A1c reductions of approximately 1.0-1.5 percentage points are common with GLP-1 receptor agonists, while tirzepatide has shown reductions of up to 2.0-2.3 percentage points in clinical trials

doi: 10.3748/wjg.v24.i7.819

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