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The mechanism involves glucose-dependent insulin secretion, meaning insulin release occurs primarily when blood glucose levels are elevated, thereby reducing the risk of hypoglycemia when used as monotherapy

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Future studies will therefore focus on expanding mechanistic validation, conducting extended safety assessments, and optimizing formulation and delivery strategies to support further translational development

Meanwhile, TB-500 helps bring repair cells to the damaged area and supports proper tissue remodeling

BMP-2 and BMP-7 FDA-approved for spinal fusion and fracture healing (recombinant protein formulations)