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10 It is thought that the iodine load may unmask hyperthyroidism in patients with multinodular goiter and subclinical Graves disease

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This study adds to a growing body of evidence suggesting that GLP-1 receptor agonistsmedications originally designed for diabetes and obesitymay have broader neuroprotective effects, said Merrill

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The precise physiological and molecular consequences of how a loss of PAM affects GLP-1 levels and signaling is likely to be complex since so many hypothalamic and peripherally secreted peptides involved in the regulation of energy homeostasis are amidated [52] and a central action of PAM in GLP-1 resistance can be ruled out [53]