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In vivo and in vitro experiments have shown that glutathione deficiency can lead to mitochondrial damage and cell death caused by an increase in the number of toxic forms of oxygen, leading to an increase in the number of free radicals

2017;233(1):R43-R51

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PMID: 22463691 | doi:10.1146/annurev-biochem-052110-115718 Mendias CL et al

Macaskill AF, Rinholm JE, Twelvetrees AE, Arancibia-Carcamo IL, Muir J, Fransson A, et al