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Indeed, the European multicenter study coordinated by Graham reports that, whereas basal hyperhomocysteinemia only shows an additive effect with hypercholesterolemia, it has a synergistic effect with both hypertension and smoking on the incidence of atherosclerotic vascular disease (Graham et al, 1997)

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24 h) is used to detect the survival rate of L929 cells after treatment with different concentrations of DESs

At low concentrations, bile acids can enhance the expression of antimicrobial peptides in the respiratory epithelium and strengthen innate immunity via activation of relevant signaling pathways (e.g., TGR5-ERK1/2)